Functional chromatographic technique for natural product isolation.

نویسندگان

  • Eric C Lau
  • Damian J Mason
  • Nicole Eichhorst
  • Pearce Engelder
  • Celestina Mesa
  • E M Kithsiri Wijeratne
  • G M Kamal B Gunaherath
  • A A Leslie Gunatilaka
  • James J La Clair
  • Eli Chapman
چکیده

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 8  شماره 

صفحات  -

تاریخ انتشار 2015